供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs816906 |
CAS号: | 154-23-4 |
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抑制剂描述: 产品名称:Cianidanol 产品别名:见爱必信官网 英文别名:Cianidanol 靶点:Flavonoids CAS:154-23-4 纯度:>98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述: Catechin((+)-Catechin; D-Catechin) is a flavan-3-ol, a type of natural phenol and antioxidant. 溶解性:DMSO 58mg/ml(199.81 mM) Water 58mg/ml(199.81 mM) 体外研究: The catechin flavonoid reduces proliferation and induces apoptosis of murine lymphoma cells LB02 through modulation of antiapoptotic proteins. Treatment of human prostate cancer cells with catechin induces apoptosis and results in effects on a variety of survival signals suggesting the potential of these compounds as chemopreventive agents for prostate cancer. Catechin is well known to inhibit cyclooxygenase activity with reported IC50 values ranging from 4O μM to 943 μM. It has also been reported to act as an inhibitor of COX-1 and COX-2 with IC50 of about 80 μM and 130 μM. 体内研究:Dietary catechin significantly delayed tumor onset. Continued intake of catechin, a potential antioxidant, prevents memory regression and DNA oxidative damage in senescence-accelerated (SAMP10) mice. It does not prolong the lifetime of SAMP10 mice, but it does delay brain senescence. (+)-Catechin inhibits intestinal tumor formation and suppresses Focal adhesion kinase activation in the Min/+ Mouse.
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