供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 98% |
货号: | abs812828 |
CAS号: | 65666-07-1 |
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抑制剂描述: 产品名称:Silymarin 产品别名:见爱必信官网 英文别名:Silymarin 靶点:Flavonoids CAS:65666-07-1 纯度:98% 外观:见爱必信官网 保存方法:Store at -20 ℃ 描述: Silymarin (Silybin B), a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver cancer. 溶解性:Ethanol:1mg/mL(2.07mM) DMSO:97 mg/mL (201.06 mM) Water 体外研究: Silymarin (Silybin B), a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver cancer. The mechanisms of action of silymarin involve different biochemical events, such as the stimulation of the synthetic rate of ribosomal RNA (rRNA) species through stimulation of polymerase I and rRNA transcription, protecting the cell membrane from radical-induced damage and blockage of the uptake of toxins such as alpha-amanitin. Silymarin can also provide substantial protection against different stages of UVB-induced carcinogenesis, possibly via its strong antioxidant properties. sup> 体内研究:LD50: Mice 391.4mg/kg (i.v.); Rats 370.1mg/kg (i.v.); Rabbits 142.3mg/kg (i.v.) sup>
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