供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 99% |
货号: | abs812899 |
CAS号: | 3681-99-0 |
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抑制剂描述: 产品名称:Puerarin 产品别名:见爱必信官网 英文别名:Puerarin 靶点:Flavonoids CAS:3681-99-0 纯度:99% 外观:见爱必信官网 保存方法:-20°C 描述: Puerarin 是一种5-HT2C受体和苯二氮位点拮抗剂。 溶解性:DMSO:86 mg/mL (206.54 mM) 体外研究: Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist. Pueraria is employed clinically to treat cardiovascular diseases in China. Another study showed that puerarin also possessed anti-cancer properties. Puerarin at 25 μM dose-dependently reduces HT-29 cellular growth with an increase of bax and decreases of c-myc and bcl-2. 体内研究:In hypercholesterolmic diet plus administration of puerarin (300 mg/kg/day, p.o.) rats, Puerarin markedly attenuated the increased total cholesterol induced by hypercholesterolmic diet in both serum and liver. LD50: Mice 738mg/kg (i.v.)
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