供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs819497 |
CAS号: | 481-53-8 |
公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抑制剂描述: 产品名称:Tangeretin 产品别名:见爱必信官网 英文别名:Tangeretin 靶点:Flavonoids CAS:481-53-8 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20° C 描述: Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and was also selected as a Notch-1 inhibitor. 溶解性:DMSO :24 mg/mL (64.45 mM) 体外研究: Tangeretin enhanced the radiosensitivity of GC cells as demonstrated by MTT and colony formation assays. Tangeretin also attenuated radiation-induced EMT, invasion and migration in GC cells, accompanied by a decrease in Notch-1, Jagged1/2, Hey-1 and Hes-1 expressions. Tangeretin triggered the upregulation of miR-410, a tumor-suppressive microRNA. Furthermore, re-expression of miR-410 prevented radiation-induced EMT and cell invasion. 体内研究:In this study, we investigated the in vivo anti-RSV activity of tangeretin in 3-week-old male BALB/c mice. A plaque reduction assay and fluorescence quantitative polymerase chain reaction (FQ-PCR) showed that tangeretin inhibited RSV replication in the lung of mice.
产品信息订购:
|
相关产品
详细地址
关注
拨打电话
留言咨询