供货周期: | 7天 |
品牌: | 爱必信 |
型号: | 98% |
货号: | abs819564 |
CAS号: | 6151-25-3 |
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抑制剂描述: 产品名称:Quercetin Dihydrate 产品别名:见爱必信官网 英文别名:Quercetin Dihydrate 靶点:Flavonoids CAS:6151-25-3 纯度:98% 外观:见爱必信官网 保存方法:Store at -20°C 描述: Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively. 溶解性:DMSO : 62 mg/mL (183.3 mM) 体外研究: Quercetin (dihydrate) is a type of plant-based chemical, or phytochemical, used as an ingredient in supplements, beverages or foods. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits[1]. Quercetin (dihydrate) is a PI3K inhibitor with IC50s of 2.4-5.4 μM. Quercetin dihydrate (Sophoretin dihydrate) strongly abrogates PI3K and Src kinases, mildly inhibits Akt1/2, and slightly affected PKC, p38 and ERK1/2. Quercetin (dihydrate) inhibits TNF-induced LDH% release, EC-dependent neutrophils adhesion to bovine pulmonary artery endothelial cells (BPAEC), and BPAEC DNA synthesis and proliferation. 体内研究:
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