Arctiin(NSC 315527)|>98%|abs810068-爱必信(上海)生物科技有限公司

Arctiin(NSC 315527)

参考价：¥415

供货周期：

一周

品牌：

爱必信

规格：

>98%

货号：

abs810068

CAS号：

20362-31-6

产品详情

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抑制剂描述：

产品名称：Arctiin(NSC 315527)

产品别名：见爱必信官网

英文别名：Arctiin(NSC 315527)

靶点：Lignans

CAS：20362-31-6

纯度：>98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述：

Arctiin, a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis.

溶解性：DMSO : 93 mg/mL (174 mM)
Ethanol : 93 mg/mL (174 mM)
Water : 37 mg/mL (69.2 mM)

体外研究：

Arctiin induces growth inhibition and dephosphorylates the tumor-suppressor retinoblastoma protein in human immortalized keratinocyte HaCaT cells. The growth inhibition caused by arctiin is associated with the downregulation of cyclin D1 protein expression. The arctiin-induced suppression of cyclin D1 protein expression occurs in various types of human tumor cells, including osteosarcoma, lung, colorectal, cervical and breast cancer, melanoma, transformed renal cells and prostate cancer.

体内研究：Arctiin has anti-cancer properties in animal models. arctiin has a remarkable anti-tumor-promoting effect as seen in a two-stage carcinogenesis test of mouse skin tumors induced by 7,12-dimethylbenzanthracene(DMBA) as an initiator and 12-Otetradecanoyl phorbol-13-acetate (TPA) as a promoter by topical and oral administration. It also has a protective effect on 2-amino-1-methyl-6-phenylimidazopyridine (PhIP)-induced carcinogenesis particularly in the mammary gland during the promotion period. Arctiin is orally effective against either IFV-inoculated normal or 5-fluorouracil (5-FU)-treated mice.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs810068	Arctiin(NSC 315527)	25mg	415.00	立即咨询
abs810068	Arctiin(NSC 315527)	200mg	1399.00	立即咨询
abs810068	Arctiin(NSC 315527)	50mg	549.00	立即咨询
abs810068	Arctiin(NSC 315527)	100mg	777.00	立即咨询

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