供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs814575 |
CAS号: | 57-10-3 |
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抑制剂描述: 产品名称:Palmitic Acid 产品别名:见爱必信官网 英文别名:Palmitic Acid 靶点:Miscellaneous CAS:57-10-3 纯度:>98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -80℃ for six months. 描述: Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity. 溶解性:DMSO :51 mg/mL (198.89 mM) 体外研究: Palmitic acid (PA) binds TLR4 via the adaptor protein MD2 and that the TLR4 signal induced by PA stimulates dendritic cells activation and maturation accompanied by a robust IL-1β response. Palmitic acid is a TLR4/MD-2 ligand. It exerts pro-inflammatory activity through TLR4. 体内研究:In a dose-dependent fashion, palmitic acid rapidly reduces mouse locomotor activity by a mechanism that did not rely on TLR4, MyD88, IL-1, IL-6 or TNFα but is dependent on fatty acid chain length. Palmitic acid induces anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism.
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