| 供货周期： | 一周 |
| 品牌： | 爱必信 |
| 规格： | ＞98% |
| 货号： | abs814575 |
| CAS号： | 57-10-3 |
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抑制剂描述： 产品名称：Palmitic Acid 产品别名：见爱必信官网 英文别名：Palmitic Acid 靶点：Miscellaneous CAS：57-10-3 纯度：＞98% 外观：见爱必信官网 保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -80℃ for six months. 描述： Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity. 溶解性：DMSO ：51 mg/mL (198.89 mM) 体外研究： Palmitic acid (PA) binds TLR4 via the adaptor protein MD2 and that the TLR4 signal induced by PA stimulates dendritic cells activation and maturation accompanied by a robust IL-1β response. Palmitic acid is a TLR4/MD-2 ligand. It exerts pro-inflammatory activity through TLR4. 体内研究：In a dose-dependent fashion, palmitic acid rapidly reduces mouse locomotor activity by a mechanism that did not rely on TLR4, MyD88, IL-1, IL-6 or TNFα but is dependent on fatty acid chain length. Palmitic acid induces anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism.
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