供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs812955 |
CAS号: | 10597-60-1 |
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抑制剂描述: 产品名称:3,4-Dihydroxyphenylethanol 产品别名:见爱必信官网 英文别名:3,4-Dihydroxyphenylethanol 靶点:Phenols CAS:10597-60-1 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20° C 描述: 3,4-Dihydroxyphenylethanol is an active ingredient that extracted from olive. It is one of the most efficient and secure antioxidant and can be used in the cardiovascular drugs。 溶解性:Soluble in water (50mg/ml) 体外研究: Hydroxytyrosol decreases the intracellular reactive oxygen species (ROS) level in MCF10A cells but not in MCF7 or MDA-MB-231 cells. Hydroxytyrosol prevents oxidative DNA damage in the three breast cell lines: MCF10A, MDA-MB-231 and MCF7 cells. It is a potent antioxidant because of its marked antioxidant activity, its ability to scavenge oxygen and nitrogen free radicals, to inhibit Low Density Lipoprotein (LDL) oxidation, platelet aggregation and endothelial cell activation and its protection against DNA damage. Hydroxytyrosol is able to reduce the synthesis of prostaglandin E2 blocking the transcription of COX-2 and 5-lipooxygenase, thereby reducing the chronic influence associated with diseases such as cancer. 体内研究:HT administration protects against hepatic I/R injury, as indicated by the decreased levels of serum aminotransferase and less parenchymal necrosis and apoptosis. Serum levels of tumor necrosis factor-α, interleukin-6, macrophage inflammatory protein 2, as well as reactive oxygen species (ROS) content in liver tissues, are all decreased by HT.
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