Chrysophanol|99%|abs817681-爱必信(上海)生物科技有限公司

Chrysophanol

参考价：¥429

供货周期：

一周

品牌：

爱必信

规格：

99%

货号：

abs817681

CAS号：

481-74-3

产品详情

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抑制剂描述：

产品名称：Chrysophanol

产品别名：见爱必信官网

英文别名：Chrysophanol

靶点：Quinones

CAS：481-74-3

纯度：99%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述：

Extracted from Rheum palmatum L.;Suitability:Boiling ethanol,benzene,chloroform,ether,acetic acid and acetone;Store the product in sealed,cool and dry condition

溶解性：DMSO : 5 mg/mL (19.66 mM), warmed

体外研究：

Chrysophanic acid (Chrysophanol) is a EGFR/mTOR pathway inhibitor. Chrysophanic acid (Chrysophanol) is a natural anthraquinone, has anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid (Chrysophanol) preferentially blocks proliferation in SNU-C5 cells but not in other cell lines (HT7, HT29, KM12C, SW480, HCT116 and SNU-C4) with low levels of EGFR expression. Chrysophanic acid (Chrysophanol) treatment in SNU-C5 cells inhibits EGF-induced phosphorylation of EGFR and suppresses activation of downstream signaling molecules, such as AKT, extracellular signal-regulated kinase (ERK) and the mammalian target of rapamycin (mTOR)/ribosomal protein S6 kinase (p70S6K). Chrysophanic acid also inhibits the replication of poliovirus types 2 and 3 (Picornaviridae) and poliovirus-induced cytopathic effects in BGM (Buffalo green monkey) kidney cells.

体内研究：

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs817681	Chrysophanol	100mg	429.00	立即咨询
abs817681	Chrysophanol	25mg	263.00	立即咨询
abs817681	Chrysophanol	50mg	404.00	立即咨询
abs817681	Chrysophanol	200mg	774.00	立即咨询

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