供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 98% |
货号: | abs817651 |
CAS号: | 4871-97-0 |
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抑制剂描述: 产品名称:Curcumol 产品别名:见爱必信官网 英文别名:Curcumol 靶点:Sesquiterpenoids CAS:4871-97-0 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述:Curcumol is a pure monomer isolated from Rhizoma Curcumaeis with antitumor activities. Extracted from Curcuma zedoaria(Berg.)Rose;Store the product in sealed,cool and dry condition 溶解性:10 mM in DMSO 体外研究: Curcumol induced cell death in human lung adenocarcinoma (ASTC-a-1) cells by inducing G(2)/M phase arrest, nuclear fragmentation, phosphatidylserine externalization and a rapid translocation of Bax from cytosol into mitochondria. While, caspases are not involved in Curcumol-induced apoptosis. Curcumol also benefits rheumatoid arthritis treatment through suppressing the fibroblast-like synoviocytes (FLS) proliferation and DNA synthesis. It attenuates PDGF-BB-induced Jak2 phosphorylation and downregulates STAT1 and STAT3 DNA-binding activities. 体内研究:
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