供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 98% |
货号: | abs822168 |
CAS号: | 473-08-5 |
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抑制剂描述: 产品名称:α-Cyperone 产品别名:见爱必信官网 英文别名:α-Cyperone 靶点:Sesquiterpenoids CAS:473-08-5 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:Alpha-cyperone is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation. which would be highly beneficial for treatment of inflammatory diseases such as AD.In vitro: The anti-inflammatory activity of alpha-cyperone is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells.Alpha-Cyperone binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter. 溶解性:In Vitro: DMSO : (insoluble or slightly soluble) 体外研究: 体内研究:
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