供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs817350 |
CAS号: | 465-21-4 |
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抑制剂描述: 产品名称:Bufalin 产品别名:见爱必信官网 英文别名:Bufalin 靶点:Steroids CAS:465-21-4 纯度:>98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述: Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in cancer cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway. 溶解性:10 mM in DMSO 体外研究: 体内研究:
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