供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 98% |
货号: | abs821169 |
CAS号: | 174402-32-5 |
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抑制剂描述: 产品名称:Edotecarin 产品别名:见爱必信官网 英文别名:Edotecarin 靶点:Topoisomerase CAS:174402-32-5 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:Edotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM. 溶解性:DMSO* 体外研究: In the presence of human colon cancer cells labeled with 3Hthymidine, edotecarin (0.6 μmol/L) increases the formation of DNA-protein complexes in a time-dependent manner. 体内研究:In the presence of human colon cancer cells labeled with 3Hthymidine, edotecarin (0.6 μmol/L) increases the formation of DNA-protein complexes in a time-dependent manner.
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