供货周期: | 一周 |
品牌: | 爱必信 |
规格: | |
货号: | abs821916 |
CAS号: | 308246-57-3 |
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抑制剂描述: 产品名称:LMP744 hydrochloride 产品别名:见爱必信官网 英文别名:LMP744 hydrochloride 靶点:Topoisomerase CAS:308246-57-3 纯度: 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:LMP744 hydrochloride (MJ-III65 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. 溶解性: 体外研究: The GI50 value of LMP744 (MJ-III-65) for NCI60 cells is 0.1 μM.LMP744 (0.1-5 μM, 3 days) induces dose-dependent accumulation of cells in the S and G2 phases of the cell cycle.Cell Cytotoxicity AssayCell Line:P388 and P388 Top1-deficient murine leukemia cells.Concentration:0.1-100 μMIncubation Time:3 daysResult:Induced dose-dependent accumulation of cells in the S and G2 phases of the cell cycle. 体内研究:The GI50 value of LMP744 (MJ-III-65) for NCI60 cells is 0.1 μM.LMP744 (0.1-5 μM, 3 days) induces dose-dependent accumulation of cells in the S and G2 phases of the cell cycle.Cell Cytotoxicity AssayCell Line:P388 and P388 Top1-deficient murine leukemia cells.Concentration:0.1-100 μMIncubation Time:3 daysResult:Induced dose-dependent accumulation of cells in the S and G2 phases of the cell cycle.
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