Crosstide

Crosstide

参考价:¥1386
供货周期: 一周
品牌: 爱必信
规格: 98%
货号: abs821159
CAS号: 171783-05-4
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抑制剂描述:

产品名称:Crosstide

产品别名:见爱必信官网

英文别名:Crosstide

靶点:Akt

CAS:171783-05-4

纯度:98%

外观:见爱必信官网

保存方法:store at -20℃ for one year(Powder)

描述:Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt.

溶解性:

体外研究:

16HBE14o? cells exposed to RV39 demonstrate a crosstide kinase activity in vitro. Serine phosphorylation of crosstide is confirmed by immunoblotting, and phosphorylation is blocked by PP2 but not by PP3. The wildtype GST-AKT2 shows significant phosphoryl transferase activity towards crosstide, reaching an initial velocity of 16 pmol phosphate/min/μg enzyme. The mutant GST-AKT2T/E,S/D displayed an initial velocity of 85 pmol phosphate/min/μg kinase for phosphorylation of Crosstide, corresponding to a 5-fold increase compared to the wildtype enzyme.

体内研究:16HBE14o? cells exposed to RV39 demonstrate a crosstide kinase activity in vitro. Serine phosphorylation of crosstide is confirmed by immunoblotting, and phosphorylation is blocked by PP2 but not by PP3. The wildtype GST-AKT2 shows significant phosphoryl transferase activity towards crosstide, reaching an initial velocity of 16 pmol phosphate/min/μg enzyme. The mutant GST-AKT2T/E,S/D displayed an initial velocity of 85 pmol phosphate/min/μg kinase for phosphorylation of Crosstide, corresponding to a 5-fold increase compared to the wildtype enzyme.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs821159   Crosstide   1mg   1386.00   立即咨询
  abs821159   Crosstide   5mg   5544.00   立即咨询

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