供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs811566 |
CAS号: | 197250-15-0 |
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抑制剂描述: 产品名称:Gap 26 产品别名:见爱必信官网 英文别名:Gap 26 靶点:Gap Junction Protein CAS:197250-15-0 纯度:>98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述: Gap 26 is a connexin mimetic peptide, corresponding to residues 63-75 of connexin 43, which is a gap junction blocker. 溶解性:Soluble to 2 mg/ml in water 体外研究: Gap 26 is corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. Gap 26 (100-300 μM) dose-dependently reduces the rhythmic responses of rabbit superior mesenteric arteries, with IC50 of 28.4 ± 3.4 μM. Gap 26 abolishes the inositol-1,4,5-trisphosphate (InsP3)-triggered ATP response and reduces the ATP release, but has no effect on gap junctional coupling. 体内研究:
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