供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs810191 |
CAS号: | 250612-42-1 |
公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抑制剂描述: 产品名称:cyclo(-RGDyK) 产品别名:见爱必信官网 英文别名:cyclo(-RGDyK) 靶点:Integrin CAS:250612-42-1 纯度:>98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述: Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. 溶解性:DMSO 100 mg/mL (117.96 mM) 体外研究: Cyclo(RGDyK) shows high affinity and selectivity for αVβ3 over αVβ5 and αIIbβ3. Cyclo(RGDyK)-conjugated micelles (TPM) facilitated the cell-specific uptake of DiI into B16-F10 cells and HUVECs via integrin-mediated endocytosis compared with Cyclo(RGDyK) -free micelles (NPM). 体内研究:In apoE?/? mice, Cyclo(RGDyK) (1 nmol, i.v.) inhibits the increase of αVβ3 integrin expression in the intima of the left stenotic carotid artery.
产品信息订购:
|
相关产品
详细地址
关注
拨打电话
留言咨询