Endothelin-2, human||abs820410-爱必信(上海)生物科技有限公司

Endothelin-2, human

参考价：¥3931

供货周期：

7天

品牌：

爱必信

货号：

abs820410

CAS号：

123562-20-9

产品详情

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抑制剂描述：

产品名称：Endothelin-2, human

产品别名：见爱必信官网

英文别名：Endothelin-2, human

靶点：ERR

CAS：123562-20-9

纯度：

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：Endothelin-2, human is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

溶解性：

体外研究：

At nanomolar concentrations, Endothelin-2 exhibits a strong and long-lasting vasoconstrictor activity characteristic of endothelin (EC50=0.52 nM). Endothelin-2 is a chemoattractant for macrophages and THP-1 monocytic cells, but not for freshly isolated monocytes. The chemotactic response to Endothelin-2 shows a typical bell-shaped response curve. Experiments with endothelin receptor antagonists shows that migration to Endothelin-2 is mediated via the ET-RB receptor. Endothelin-2 expression by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia.

体内研究：At nanomolar concentrations, Endothelin-2 exhibits a strong and long-lasting vasoconstrictor activity characteristic of endothelin (EC50=0.52 nM). Endothelin-2 is a chemoattractant for macrophages and THP-1 monocytic cells, but not for freshly isolated monocytes. The chemotactic response to Endothelin-2 shows a typical bell-shaped response curve. Experiments with endothelin receptor antagonists shows that migration to Endothelin-2 is mediated via the ET-RB receptor. Endothelin-2 expression by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia.

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产品货号	产品名称	规格	价格	大包装及货期
abs820410	Endothelin-2, human	500ug	3931.00	立即咨询

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