供货周期: | 一周 |
品牌: | 爱必信 |
规格: | |
货号: | abs822475 |
CAS号: | 62982-31-4 |
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抑制剂描述: 产品名称:Allergen Gal d 4 (46-61), chicken 产品别名:见爱必信官网 英文别名:Allergen Gal d 4 (46-61), chicken 靶点:Bacterial CAS:62982-31-4 纯度: 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide. 溶解性:10 mM in H2O 体外研究: Allergen Gal d 4 (46-61), chicken (HEL(46-61)) contains the immunodominant epitope recognized by mice of the k haplotype. The binding is shown to be specific, with a Kd of approximately 2 uM. The direct binding of a hen egg white lysozyme peptide, Allergen Gal d 4 (46-61), is examined to membrane I-Ak (protein encoded in the A locus of the I region) molecules in the presence of detergent. A number of synthetic peptide derivatives, which do not stimulate our T-cell reactive hybridomas, compete for the binding of Allergen Gal d 4 (46-61) to I-Ak and also inhibit the functional presentation of Allergen Gal d 4 (46-61). Inhibitors include a peptide lacking a tyrosine at position 53 and a peptide corresponding to the autologous lysozyme peptide. Presentation is examined with cells or with supported planar phospholipid membranes bearing only I-Ak and Allergen Gal d 4 (46-61). 体内研究:Allergen Gal d 4 (46-61), chicken (HEL(46-61)) contains the immunodominant epitope recognized by mice of the k haplotype. The binding is shown to be specific, with a Kd of approximately 2 uM. The direct binding of a hen egg white lysozyme peptide, Allergen Gal d 4 (46-61), is examined to membrane I-Ak (protein encoded in the A locus of the I region) molecules in the presence of detergent. A number of synthetic peptide derivatives, which do not stimulate our T-cell reactive hybridomas, compete for the binding of Allergen Gal d 4 (46-61) to I-Ak and also inhibit the functional presentation of Allergen Gal d 4 (46-61). Inhibitors include a peptide lacking a tyrosine at position 53 and a peptide corresponding to the autologous lysozyme peptide. Presentation is examined with cells or with supported planar phospholipid membranes bearing only I-Ak and Allergen Gal d 4 (46-61).
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