E3 ligase Ligand-Linker Conjugates 10|98%|abs821279-爱必信(上海)生物科技有限公司

E3 ligase Ligand-Linker Conjugates 10

参考价：¥4410

供货周期：

7天

品牌：

爱必信

型号：

98%

货号：

abs821279

CAS号：

1835705-57-1

产品详情

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抑制剂描述：

产品名称：E3 ligase Ligand-Linker Conjugates 10

产品别名：见爱必信官网

英文别名：E3 ligase Ligand-Linker Conjugates 10

靶点：VHL/PROTAC

CAS：1835705-57-1

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：E3 ligase Ligand-Linker Conjugates 10 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

溶解性：

体外研究：

E3 ligase Ligand-Linker Conjugates 10 uses the VHL ligand. The linker is 6-2-2. The linkers contain a mixture of hydrophobic and hydrophilic moieties to balance the hydrophobicity/hydrophilicity of the resulting hybrid compounds. PROTACs that induce the degradation of an oncogenic tyrosine kinase, BCR-ABL has been developed. E3 ligase Ligand-Linker Conjugates 10 can be attached to potent TKIs (bosutinib and dasatinib) that mediate the degradation of c-ABL and BCR-ABL by hijacking either CRBN or VHL E3 ubiquitin ligase .

体内研究：E3 ligase Ligand-Linker Conjugates 10 uses the VHL ligand. The linker is 6-2-2. The linkers contain a mixture of hydrophobic and hydrophilic moieties to balance the hydrophobicity/hydrophilicity of the resulting hybrid compounds. PROTACs that induce the degradation of an oncogenic tyrosine kinase, BCR-ABL has been developed. E3 ligase Ligand-Linker Conjugates 10 can be attached to potent TKIs (bosutinib and dasatinib) that mediate the degradation of c-ABL and BCR-ABL by hijacking either CRBN or VHL E3 ubiquitin ligase .

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs821279	E3 ligase Ligand-Linker Conjugates 10	100mg	4410.00	立即咨询
abs821279	E3 ligase Ligand-Linker Conjugates 10	500mg	17010.00	立即咨询

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