8-Azaguanine

8-Azaguanine

参考价:¥473
供货周期: 一周
品牌: 爱必信
规格: >98%
货号: abs813494
CAS号: 134-58-7
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抑制剂描述:

产品名称:8-Azaguanine

产品别名:见爱必信官网

英文别名:8-Azaguanine

靶点:Nucleoside Antimetabolite/Analog

CAS:134-58-7

纯度:>98%

外观:见爱必信官网

保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述:

Azaguanine-8 is a purine analogs showing antineoplastic activity by competing with guanine in the metabolism. 8-Azaguanine is a purine analogue that shows antineoplastic activity. Azaguanine-8 functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, so that it can inhibite cellular growth. Azaguanine-8 has been reported that a study of the in vivo metabolism of 8-azaguanine-2-C 14 by mouse neoplasms that are susceptible or resistant to growth inhibition by 8-azagnanine. The results show that the growth of those neoplasms which convert significant amounts of 8-azaguanine to 8-azaguanylic acid is inhibited by 8-azaguanine.

溶解性:DMSO :6 mg/mL (39.44 mM)

体外研究:

8-Azaguanine is a purine analogue that shows antineoplastic activity. It functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth.

体内研究:A study of the in vivo metabolism of 8-azaguanine-2-C 14 by mouse neoplasms that are susceptible or resistant to growth inhibition by 8-azagnanine have been reported. The results show that the growth of those neoplasms which convert significant amounts of 8-azaguanine to 8-azaguanylic acid is inhibited by 8-azaguanine.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs813494   8-Azaguanine   25mg   473.00   立即咨询
  abs813494   8-Azaguanine   50mg   683.00   立即咨询
  abs813494   8-Azaguanine   100mg   1208.00   立即咨询

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