Tiplaxtinin(PAI-039)|>98%|abs810239-爱必信(上海)生物科技有限公司

Tiplaxtinin(PAI-039)

参考价：¥772

供货周期：

一周

品牌：

爱必信

规格：

>98%

货号：

abs810239

CAS号：

393105-53-8

产品详情

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抑制剂描述：

产品名称：Tiplaxtinin(PAI-039)

产品别名：见爱必信官网

英文别名：Tiplaxtinin(PAI-039)

靶点：PAI-1

CAS：393105-53-8

纯度：>98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述：Inhibitor of plasminogen activator inhibitor-1 (PAI-1)

溶解性：DMSO 72 mg/mL (163.86 mM)
Ethanol 18 mg/mL warmed (40.96 mM)
2.0% Tween 80+0.5% methylcellulose 30mg/mL

体外研究：

In a panel of human bladder cell lines, PAI-1 results in the reduction of cellular proliferation, cell adhesion, and colony formation, and the induction of apoptosis and anoikis.

体内研究：In a rat carotid thrombosis model, Tiplaxtinin (1 mg/kg, p.o.) increases time to occlusion and prevents the carotid blood flow reduction. In C57BL/6J mice, (1 mg/g chow) attenuates Ang II-induced aortic remodeling. In untreated type 1 diabetic mice, Tiplaxtinin (p.o.) restores skeletal muscle regeneration. In athymic mice bearing human cancer cell line T24 and HeLa xenografts, Tiplaxtinin (1 mg/kg, p.o.) reduces tumor xenograft growth, associated with a reduction in tumor angiogenesis, a reduction in cellular proliferation, and an increase in apoptosis.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs810239	Tiplaxtinin(PAI-039)	5mg	772.00	立即咨询
abs810239	Tiplaxtinin(PAI-039)	10mg	972.00	立即咨询
abs810239	Tiplaxtinin(PAI-039)	50mg	4216.00	立即咨询
abs810239	Tiplaxtinin(PAI-039)	100mg	6417.00	立即咨询

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