SHIN1|98%|abs821634-爱必信(上海)生物科技有限公司

SHIN1

参考价：¥6930

供货周期：

一周

品牌：

爱必信

规格：

98%

货号：

abs821634

CAS号：

2146095-85-2

产品详情

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抑制剂描述：

产品名称：SHIN1

产品别名：见爱必信官网

英文别名：SHIN1

靶点：Transferase

CAS：2146095-85-2

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：SHIN1 is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC50s of 5 and 13 nM, respectively, in an in vitro assay.

溶解性：

体外研究：

SHIN1 inhibits human SHIN1 SHMT1/2 with IC50s of 5 and 13 nM, respectively in an in vitro assay. SHIN1 inhibits the growth of SHMT2 deletion HCT-116 cells with an IC50 of 10 nM. SHIN1 inhibits SHMT1/2 in HCT-116 cells. SHIN1 is particularly active against B-cell malignancies. SHIN1 blocks cell growth through a progressive depletion of purines, leading to loss of nucleotide triphosphates.

体内研究：SHIN1 inhibits human SHIN1 SHMT1/2 with IC50s of 5 and 13 nM, respectively in an in vitro assay. SHIN1 inhibits the growth of SHMT2 deletion HCT-116 cells with an IC50 of 10 nM. SHIN1 inhibits SHMT1/2 in HCT-116 cells. SHIN1 is particularly active against B-cell malignancies. SHIN1 blocks cell growth through a progressive depletion of purines, leading to loss of nucleotide triphosphates.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs821634	SHIN1	5mg	6930.00	立即咨询
abs821634	SHIN1	25mg	22050.00	立即咨询

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