供货周期: | 一周 |
品牌: | 爱必信 |
规格: | |
货号: | abs821706 |
CAS号: | 2234281-75-3 |
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抑制剂描述: 产品名称:JI051 产品别名:见爱必信官网 英文别名:JI051 靶点:Notch CAS:2234281-75-3 纯度: 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:JI051 is a stabilizer for the Hes1-PHB2 interaction, interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene HesAnti-cancer activity. 溶解性: 体外研究: JI051 causes G2/M cell-cycle arrest.JI051 (0.1-10 μM, 24 hours) significantly inhibits cell proliferation of HEK293 cells, with an EC50 of 0.3 μM.Cell Proliferation AssayCell Line:HEK293 cellsConcentration:0.1-10 μMIncubation Time:24 hoursResult:Dose-dependently inhibits the proliferation of HEK293 cells at low concentrations. 体内研究:JI051 causes G2/M cell-cycle arrest.JI051 (0.1-10 μM, 24 hours) significantly inhibits cell proliferation of HEK293 cells, with an EC50 of 0.3 μM.Cell Proliferation AssayCell Line:HEK293 cellsConcentration:0.1-10 μMIncubation Time:24 hoursResult:Dose-dependently inhibits the proliferation of HEK293 cells at low concentrations.
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