供货周期: | 7天 |
品牌: | 爱必信 |
货号: | abs820870 |
CAS号: | 149400-88-4 |
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抑制剂描述: 产品名称:Sardomozide 产品别名:见爱必信官网 英文别名:Sardomozide 靶点:Others CAS:149400-88-4 纯度: 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. 溶解性:DMSO* 体外研究: Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells. 体内研究:Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.
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