| 供货周期： | 7天 |
| 品牌： | 爱必信 |
| 型号： | ≥98% |
| 货号： | abs819469 |
| CAS号： | 337932-29-3 |
| 公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!
抑制剂描述： 产品名称：Cuspin-1 产品别名：见爱必信官网 英文别名：Cuspin-1 靶点：Others CAS：337932-29-3 纯度：≥98% 外观：见爱必信官网 保存方法：Store at -20℃ 描述： The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA). Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 μM. Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Raf-MEK signaling, which results in an increased rate of SMN translation. 溶解性：DMSO ：16mg/ml 体外研究： 体内研究：
产品信息订购：
|
相关产品
工商信息
信息已认证
联系方式
详细地址
关注
拨打电话
留言咨询
