WAY-204688||abs822729-爱必信(上海)生物科技有限公司

WAY-204688

参考价：¥7308

供货周期：

一周

品牌：

爱必信

规格：

货号：

abs822729

CAS号：

796854-35-8

产品详情

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抑制剂描述：

产品名称：WAY-204688

产品别名：见爱必信官网

英文别名：WAY-204688

靶点：NF-kB

CAS：796854-35-8

纯度：

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：WAY-204688 is an estrogen receptor (ER-α) selective, orally active inhibitor of NF-κB transcriptional activity with an IC50 of 122?±?30 nM for NF-κB-luciferase (NF-κB-luc) in HAECT-1 cells.

溶解性：DMSO*

体外研究：

WAY-204688 is ER-dependenrt (activity seen only when hER is coexpressed with NF-κB-luciferase in human aortic endothelial cell lines (HAECT-1) cells). The interaction of WAY-204688 with ERα and ERβ is examined in vitro. WAY-204688 displaces [3H]E2 from the ERα ligand binding domain protein (LBD) with IC50=2.43 μM and from the ERβ ligand binding domain protein (LBD) with IC50=1.5 μM.

体内研究：WAY-204688 is ER-dependenrt (activity seen only when hER is coexpressed with NF-κB-luciferase in human aortic endothelial cell lines (HAECT-1) cells). The interaction of WAY-204688 with ERα and ERβ is examined in vitro. WAY-204688 displaces [3H]E2 from the ERα ligand binding domain protein (LBD) with IC50=2.43 μM and from the ERβ ligand binding domain protein (LBD) with IC50=1.5 μM.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs822729	WAY-204688	1mg	7308.00	立即咨询
abs822729	WAY-204688	5mg	14490.00	立即咨询

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