GSK'547|98%|abs821696-爱必信(上海)生物科技有限公司

GSK'547

参考价：¥1517

供货周期：

7天

品牌：

爱必信

型号：

98%

货号：

abs821696

CAS号：

2226735-55-1

产品详情

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抑制剂描述：

产品名称：GSK'547

产品别名：见爱必信官网

英文别名：GSK'547

靶点：RIP Kinase

CAS：2226735-55-1

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：GSK547, a highly selective and potent RIP1 inhibitor, inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.

溶解性：

体外研究：

GSK547 (0.1-100000 nM; 24 hours) pretreats L929 cells with recombinant TNFα and zVAD at various doses for 30 min, then cell death is induced with an IC50 of 32 nM after 24 hours.GSK547 up-regulates STAT1 signaling in bone marrow-derived macrophages (BMDM).Cell Viability AssayCell Line:L929 cells (Mouse L-cells NCTC 929)Concentration:0.1 nM; 10 nM; 1000 nM; 100000 nMIncubation Time:24 hoursResult:Reduced viability of L929 cells after co-treatment with TNFα and zVAD with an IC50 of 32 nM.

体内研究：GSK547 (0.1-100000 nM; 24 hours) pretreats L929 cells with recombinant TNFα and zVAD at various doses for 30 min, then cell death is induced with an IC50 of 32 nM after 24 hours.GSK547 up-regulates STAT1 signaling in bone marrow-derived macrophages (BMDM).Cell Viability AssayCell Line:L929 cells (Mouse L-cells NCTC 929)Concentration:0.1 nM; 10 nM; 1000 nM; 100000 nMIncubation Time:24 hoursResult:Reduced viability of L929 cells after co-treatment with TNFα and zVAD with an IC50 of 32 nM.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs821696	GSK'547	2mg	1517.00	立即咨询

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