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抑制剂描述： 产品名称：8-Azaguanine 产品别名：见爱必信官网 英文别名：8-Azaguanine 靶点：Nucleoside Antimetabolite/Analog CAS：134-58-7 纯度：>98% 外观：见爱必信官网 保存方法：store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述： Azaguanine-8 is a purine analogs showing antineoplastic activity by competing with guanine in the metabolism. 8-Azaguanine is a purine analogue that shows antineoplastic activity. Azaguanine-8 functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, so that it can inhibite cellular growth. Azaguanine-8 has been reported that a study of the in vivo metabolism of 8-azaguanine-2-C 14 by mouse neoplasms that are susceptible or resistant to growth inhibition by 8-azagnanine. The results show that the growth of those neoplasms which convert significant amounts of 8-azaguanine to 8-azaguanylic acid is inhibited by 8-azaguanine. 溶解性：DMSO ：6 mg/mL (39.44 mM) 体外研究： 8-Azaguanine is a purine analogue that shows antineoplastic activity. It functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. 体内研究：A study of the in vivo metabolism of 8-azaguanine-2-C 14 by mouse neoplasms that are susceptible or resistant to growth inhibition by 8-azagnanine have been reported. The results show that the growth of those neoplasms which convert significant amounts of 8-azaguanine to 8-azaguanylic acid is inhibited by 8-azaguanine.
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