磷酸化T淋巴细胞受体抗体

磷酸化T淋巴细胞受体抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing 磷酸化T淋巴细胞受体抗体chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

磷酸化T淋巴细胞受体抗体Also known as:

Bcr (phospho Y177); Bcr(Phospho-Tyr177); ALL; BCR 1; BCR/ABL FUSION GENE INCLUDED; BCR/FGFR1 FUSION GENE INCLUDED; BCR/PDGFRA FUSION GENE INCLUDED; BCR1; breakpoint cluster region;磷酸化T淋巴细胞受体抗体 CML; PHL; BCR_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, .

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Immunogen: KLH conjugated Synthesisedphosphopeptide derived from human Bcr around the phosphorylation site of Tyr177 [PF(p-Y)VN].

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磷酸化T淋巴细胞受体抗体Predicted Molecular Weight: 143kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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