细胞凋亡敏感性基因抗体

?细胞凋亡敏感性基因抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds 细胞凋亡敏感性基因抗体importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

细胞凋亡敏感性基因抗体Also known as:

Cellular Apoptosis Susceptibility; exportin-2; CAS; Cellular apoptosis susceptibility protein; Chromosome segregation 1 (yeast homolog) like; Chromosome segregation 1 Like; Chromosome segregation 1 like protein; Chromosome segregation gene CSE1; CSE 1; CSE 1 chromosome segregation 1 like; CSE 1 chromosome segregation 1 like protein; CSE 1L; CSE1; CSE1 chromosome segregation 1 like;细胞凋亡敏感性基因抗体 CSE1 chromosome segregation 1 like protein; CSE1L; Exp 2; Exp2; Exportin 2; Exportin2; Exportin-2; Importin alpha re exporter; XPO2_HUMAN; Chromosome segregation 1-like protein; Importin-alphare-exporter.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human CAS.

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细胞凋亡敏感性基因抗体Predicted Molecular Weight: 107kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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