供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL12323R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 细胞粘附分子相关蛋白/癌基因下调蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells.细胞粘附分子相关蛋白/癌基因下调蛋白抗体 CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch.细胞粘附分子相关蛋白/癌基因下调蛋白抗体 The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein.
Also known as:
CDO; CDON; Cell adhesion molecule-related/down-regulated by oncogenes; CDON_HUMAN.
细胞粘附分子相关蛋白/癌基因下调蛋白抗体Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human CDON.
●
细胞粘附分子相关蛋白/癌基因下调蛋白抗体Predicted Molecular Weight: 136kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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