供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL1454R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 表皮生长因子受体3抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with 表皮生长因子受体3抗体other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers 表皮生长因子受体3抗体including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized.
表皮生长因子受体3抗体Also known as:
ErbB 3; ErbB-3; c erbB 3; c-erbB3; ERBB3; cerbB3; ERBB3 protein; cerbB; 3erbB3 S; Glial growth factor receptor; HER 3; HER3; LCCS2; MDA BF 1; MGC88033; p180 ErbB3; p45 sErbB3; p85 sErbB3; proto-oncogene-; receptor tyrosine protein kinase ERB3 [precursor]; Receptor tyrosine protein kinase erbB 3; Receptor tyrosine protein kinase erbB3; Tyrosine kinase type cell surface receptor HER3; V erb b2 avian erythroblastic leukemia viral oncogene homolog 3; v erb b2 erythroblastic leukemia viral oncogene homolog 3 (avian); v erb b2 erythroblastic leukemia viral oncogene homolog 3; ERBB3_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from the middle of .
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表皮生长因子受体3抗体Predicted Molecular Weight: 147kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl130Bo01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
kl130Hu01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
kl130Mu01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
kl130Po01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
kl130Ra01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
kl130Rb51组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
kl131Bo01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)
kl131Fi01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)
kl131Hu01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)
kl131Mu01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)
kl131Po01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)
kl131Rb51转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)
kl132Hu01脂联素受体2(ADIPOR2)多克隆抗体Polyclonal Antibody to Adiponectin Receptor 2 (ADIPOR2)
kl132Ra01脂联素受体2(ADIPOR2)多克隆抗体Polyclonal Antibody to Adiponectin Receptor 2 (ADIPOR2)
kl134Bo01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)
kl134Ca01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)
kl134Hu01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)
kl134Mu01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)
kl134Po01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)
kl134Ra01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)
kl134Rb51肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)
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