表皮生长因子受体III型突变体抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 表皮生长因子受体III型突变体抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. 表皮生长因子受体III型突变体抗体EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

表皮生长因子受体III型突变体抗体Also known as:

GFRvIII; Epidermal growth factor receptor variant type Ⅲ; epidermal growth factor receptor isoform a variant.

Specificity:

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Rabbit Polyclonal IgG, 表皮生长因子受体III型突变体抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human EGFRvIII.

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Predicted Molecular Weight: 120kDa.

表皮生长因子受体III型突变体抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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