肌动蛋白结合蛋白Fascin3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 肌动蛋白结合蛋白Fascin3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Cell adhesion to extracellular matrix is an important physiological stimulus for organization of the Actin-based cytoskeleton. Adhesion to the matrix glycoprotein Thrombospondin 1 triggers the sustained formation of F-Actin microspikes that contain the Actin-bundling protein Fascin. These structures are also implicated in cell migration, which may be an 肌动蛋白结合蛋白Fascin3抗体important function of Thrombospondin 1 in tissue remodelling and wound repair. Fascin bundles Actin microfilaments within dynamic cellular structures such as microspikes, stress fibers and membrane ruffles. Fascin could serve as a prognostic factor for abnormal ovarian epithelial pathology and could be a novel target for the treatment of ovarian cancer. Fascin, an Actin-bundling protein, identifies dendritic cells in the blood and in tissues.

肌动蛋白结合蛋白Fascin3抗体Also known as:

Fascin (testis); Fascin 3; Fascin homolog 3 actin bundling protein testicular (Strongylocentrotus purpuratus) ; Fascin homolog 3 actin bundling protein testicular; Fascin3; FSCN 3; FSCN3; MGC94950; Testis fascin; FSCN3_HUMAN.

Specificity:

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Rabbit Polyclonal IgG肌动蛋白结合蛋白Fascin3抗体, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human Fascin-3.

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Predicted Molecular Weight: 57kDa.

肌动蛋白结合蛋白Fascin3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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