肽基脯氨酰顺反异构酶FKBP11抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 肽基脯氨酰顺反异构酶FKBP11抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. 肽基脯氨酰顺反异构酶FKBP11抗体Immunophilins have also been implicated in protein folding and trafficking within the endoplasmic reticulum (ER). FKBP11 (FK506-binding protein 11), also known as FKBP19 or peptidyl-prolyl cis-trans isomerase FKBP11, is a 201 amino acid single-pass membrane protein belonging to the FKBP-type PPIase family, a group of proteins known to catalyze the folding of proline-containing 肽基脯氨酰顺反异构酶FKBP11抗体polypeptides. Containing one PPIase FKBP-type domain, FKBP11 is expressed in secretory tissues such as pancreas, pituitary, stomach, lymph node and salivary gland, and is encoded by a gene that maps to human chromosome 12q13.12. FK506 and rapamycin are known to inhibit FKBP11’s peptidyl-prolyl isomerase activity.

Also known as:

19 kDa FK506 binding protein; 19 kDa FK506-binding protein; 19 kDa FKBP; FK506 binding protein 11 (19 kDa);肽基脯氨酰顺反异构酶FKBP11抗体 FK506 binding protein 11; FK506-binding protein 11; FKB11_HUMAN; FKBP 19; FKBP-11; FKBP-19; Fkbp11; FKBP19; MGC54182; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP11; PPIase; PPIase FKBP11; Rotamase.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human FKBP11.

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肽基脯氨酰顺反异构酶FKBP11抗体Predicted Molecular Weight: 19kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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