脊髓性肌萎缩症蛋白Gemin6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 脊髓性肌萎缩症蛋白Gemin6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product 脊髓性肌萎缩症蛋白Gemin6抗体of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).

脊髓性肌萎缩症蛋白Gemin6抗体Also known as:

FLJ23459; Gemin6; Gemin-6; Gem (nuclear organelle) associated protein 6; Gem-associated protein 6; GEMI6; GEMI6_HUMAN; Gemin-6; GEMIN6; SIP2.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, 脊髓性肌萎缩症蛋白Gemin6抗体Mouse, Rat, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human Gemin 6.

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Predicted Molecular Weight: 19kDa.

脊髓性肌萎缩症蛋白Gemin6抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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