供货周期: | 现货 |
品牌: | 康朗生物 |
型号: | 0.1ml/0.2ml |
货号: | KL13363R |
Quantity size:
0.2ml
Concentration:
1mg/ml 间隙连结蛋白46/白内障相关蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
?The connexin family of proteins form hexameric complexes called “connexons” that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane α-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key 间隙连结蛋白46/白内障相关蛋白抗体functional differences arise from specific amino acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is affected. For instance, deletion of the gene encoding connexin 46, normally expressed in the lens, produces severe cataracts.
间隙连结蛋白46/白内障相关蛋白抗体Also known as:
CAE3; Connexin 46; Connexin-46; Connexin46; Cx46; CXA3_HUMAN; CZP3; Gap junction alpha 3 protein; Gap junction alpha-3 protein; Gap junction protein, alpha 3, 46kD (connexin 46); Gap junction protein, alpha 3, 46kDa (connexin 46); Gap junction protein, alpha 3, 46kDa; Gja3.
Specificity:
●
Rabbit Polyclonal IgG, 间隙连结蛋白46/白内障相关蛋白抗体affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human GJA3/Con.
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Predicted Molecular Weight: 47kDa.
间隙连结蛋白46/白内障相关蛋白抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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