人类乳头状瘤病毒16/18 E6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 人类乳头状瘤病毒16/18 E6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Human Papilloma virus (HPV) is responsible for the development of type and tissue specific papilloma in the oral cavity and in the larynx. In the skin papilloma virus can cause different types of warts and in the ano-genital region it is associated with condyloma or carcinoma. HPV types 1,6 and 11 usually are associated with benign transformations of the t人类乳头状瘤病毒16/18 E6抗体issues, while e.g. HPV types 16, 18 and 31 seem to be responsible for the development of some carcinoma like cervical carcinoma. The role of HPV in non-melanoic tumours of the 人类乳头状瘤病毒16/18 E6抗体skin is under discussion.
Protein E6 is a Transcriptional transactivator, binding double stranded DNA. It has transforming activity inactivating, with E6-AP ubiquitin-protein ligase, the human TP53/p53 tumor suppressor protein by targeting it for degradation.

Also known as:

HPV16+HPV18 E6; HPV16/18 protein; Human Papilloma virus; E6; Human papillomavirus type 16 E6; Human papillomavirus type 18 E6; Protein E6 .

Specificity:

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Rabbit Polyclonal IgG, 人类乳头状瘤病毒16/18 E6抗体affinity purified by Protein A.

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Reacts with: HPV16/HPV18.

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Immunogen: Synthetic peptide from the HPV16 E6 + HPV18 E6 conjugated to.

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Predicted Molecular Weight: 11kDa.

人类乳头状瘤病毒16/18 E6抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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