人类乳头状瘤病毒18 E6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 人类乳头状瘤病毒18 E6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown 人类乳头状瘤病毒18 E6抗体that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.

人类乳头状瘤病毒18 E6抗体Also known as:

E6; Human Papilloma Virus; Human papillomavirus type 18 E6; Human papillomavirus type 18 (E6); Human papillomavirus type 18 E6; Human papillomavirus type 18 E6 protein; Protein E6; HPV18 E6 protein; VE6_HPV18.

Specificity:

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Rabbit Polyclonal IgG,人类乳头状瘤病毒18 E6抗体 affinity purified by Protein A.

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Reacts with: HPV18.

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Immunogen: Synthetic peptide from the HPV18 E6 protein conjugated to KL.

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人类乳头状瘤病毒18 E6抗体Predicted Molecular Weight: 11kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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