环化核苷酸调控阳离子通道蛋白亚型2/4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml环化核苷酸调控阳离子通道蛋白亚型2/4抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Hyperpolarization activated cation channels of the HCN gene family such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. HCN2 is a member of a family of pacemaker channels activated by hyperpolarization and regulated by cyclic nucleotides. HCN1 and HCN2 play an important role for motor learning and neuronal integration by cerebellar Purkinje cells; as well as, shaping autonomous activity of single neurons环化核苷酸调控阳离子通道蛋白亚型2/4抗体 and the periodicity of network oscillations. HCN2 is highly abundant in mamillary bodies, pontine nucleus, ventral cochlear nucleus, and nucleus of the trapezoid body. HCN4 is another 环化核苷酸调控阳离子通道蛋白亚型2/4抗体member of the family of hyperpolarization activated and cyclic nucleotide gated channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node.

Also known as:

HCN2+HCN4; HCN2 / HCN4; HCN2+4; HCN2/4; BCNG 2; Brain cyclic nucleotide gated channel 2; HAC 1; HCN 4; 环化核苷酸调控阳离子通道蛋白亚型2/4抗体HCN 2; Hyperpolarization activated cyclic nucleotide gated potassium channel 4;HCN2_HUMAN; HCN4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human HCN2 + H.

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环化核苷酸调控阳离子通道蛋白亚型2/4抗体Predicted Molecular Weight: 97+129kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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