供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL17385R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 人类乳头状瘤病毒HPV116 gp2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional 人类乳头状瘤病毒HPV116 gp2抗体activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows t 人类乳头状瘤病毒HPV116 gp2抗体he virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription
Also known as:
Protein E7
Specificity:
●
Rabbit Polyclonal IgG, 人类乳头状瘤病毒HPV116 gp2抗体affinity purified by Protein A.
●
Reacts with: Human, Human Papillomavirus (HPV).
●
Immunogen: KLH conjugated synthetic peptide derived from human HPV116 g.
●
Predicted Molecular Weight: 11kDa.
人类乳头状瘤病毒HPV116 gp2抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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