胰岛素受体底物-1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 胰岛素受体底物-1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, 胰岛素受体底物-1抗体 although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.

 胰岛素受体底物-1抗体Also known as:

HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS-1; IRS 1; IRS1; OTTHUMP00000164234; IRS1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,  胰岛素受体底物-1抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, .

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Immunogen: KLH conjugated synthetic peptide derived from rat IRS-1 (115.

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Predicted Molecular Weight: 137kDa.

 胰岛素受体底物-1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 

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kl373Ra01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)

kl374Ra01GATA结合蛋白4(GATA4)多克隆抗体Polyclonal Antibody to GATA Binding Protein 4 (GATA4)

kl376Hu01辅肌动蛋白α2(ACTN2)多克隆抗体Polyclonal Antibody to Actinin Alpha 2 (ACTN2)

kl376Mu01辅肌动蛋白α2(ACTN2)多克隆抗体Polyclonal Antibody to Actinin Alpha 2 (ACTN2)

kl380Bo01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Hu01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Mu01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Ra01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl382Hu01蛋白激酶Bγ(PKBγ)多克隆抗体Polyclonal Antibody to Protein Kinase B Gamma (PKBg)

kl383Hu01磷酸肌醇-3-激酶2α肽(PI3K2α)多克隆抗体Polyclonal Antibody to Phosphoinositide-3-Kinase Class-2-Alpha Polypeptide (PIK3C2a)

kl383Mu01磷酸肌醇-3-激酶2α肽(PI3K2α)多克隆抗体Polyclonal Antibody to Phosphoinositide-3-Kinase Class-2-Alpha Polypeptide (PIK3C2a)

kl384Hu01白介素23(IL23)多克隆抗体Polyclonal Antibody to Interleukin 23 (IL23)

kl384Mu01白介素23(IL23)多克隆抗体Polyclonal Antibody to Interleukin 23 (IL23)

kl384Ra01白介素23(IL23)多克隆抗体Polyclonal Antibody to Interleukin 23 (IL23)

kl385Hu01白介素27(IL27)多克隆抗体Polyclonal Antibody to Interleukin 27 (IL27)

kl385Ra01白介素27(IL27)多克隆抗体Polyclonal Antibody to Interleukin 27 (IL27)

kl389Mu01补体成分4a(C4a)多克隆抗体Polyclonal Antibody to Complement Component 4a (C4a)

kl389Ra01补体成分4a(C4a)多克隆抗体Polyclonal Antibody to Complement Component 4a (C4a)

Optimal working dilutions must be determined by the end user.