磷酸化单丝氨酸蛋白激酶2抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化单丝氨酸蛋白激酶2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably磷酸化单丝氨酸蛋白激酶2抗体 mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

磷酸化单丝氨酸蛋白激酶2抗体Also known as:

LIM Kinase 1 (phospho T505); p-LIM Kinase 1 (phospho T505); LIM domain kinase 2; LIMK 2; LIMK-2; LIMK2; LIMK2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,磷酸化单丝氨酸蛋白激酶2抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human LIM Kinase 1 around the phosphorylation site of Thr505.

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磷酸化单丝氨酸蛋白激酶2抗体Predicted Molecular Weight: 70kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl040Hu01趋化因子C-X3-C-基元配体1(CX3CL1)多克隆抗体Polyclonal Antibody to Chemokine C-X3-C-Motif Ligand 1 (CX3CL1)

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kl041Mu01中性粒细胞激活蛋白3(NAP3)多克隆抗体Polyclonal Antibody to Neutrophil Activating Protein 3 (NAP3)

kl041Ra01中性粒细胞激活蛋白3(NAP3)多克隆抗体Polyclonal Antibody to Neutrophil Activating Protein 3 (NAP3)

kl042Hu01粒细胞集落刺激因子(GCSF)多克隆抗体Polyclonal Antibody to Colony Stimulating Factor 3, Granulocyte (GCSF)

kl042Mu01粒细胞集落刺激因子(GCSF)多克隆抗体Polyclonal Antibody to Colony Stimulating Factor 3, Granulocyte (GCSF)

kl042Ra01粒细胞集落刺激因子(GCSF)多克隆抗体Polyclonal Antibody to Colony Stimulating Factor 3, Granulocyte (GCSF)

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kl043Ra01胶质细胞系来源神经营养因子(GDNF)多克隆抗体Polyclonal Antibody to Glial Cell Line Derived Neurotrophic Factor (GDNF)

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kl045Hu01粒细胞巨噬细胞集落刺激因子(GMCSF)多克隆抗体Polyclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)

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kl045Ra01粒细胞巨噬细胞集落刺激因子(GMCSF)多克隆抗体Polyclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)

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kl046Mu01糖蛋白130(gp130)多克隆抗体Polyclonal Antibody to Glycoprotein 130 (gp130)

kl046Ra01糖蛋白130(gp130)多克隆抗体Polyclonal Antibody to Glycoprotein 130 (gp130)

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