天冬氨酰tRNA连接酶2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 天冬氨酰tRNA连接酶2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

SLM5 (mitochondrial asparaginyl-tRNA synthetase, Asparagine-tRNA ligase) is a mitochondrial protein encoded by the human gene NARS2. AsnRS belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl tRNA synthetases (aaRS) are enzymes that catalyze the esterification of a specific amino acid or its precursor to its compatible cognate tRNA to form an aminoacyl-tRNA. The synthetase first binds ATP and the corresponding amino acid or 天冬氨酰tRNA连接酶2抗体its precursor to form an aminoacyl-adenylate and release inorganic pyrophosphate (PPi). The adenylate-aaRS complex then binds the appropriate tRNA molecule, and the amino acid is transferred from the aa-AMP to either the 2'- or 3'-OH of the last tRNA base (A76) at the 3'-end. Some天冬氨酰tRNA连接酶2抗体 synthetases also mediate a proofreading reaction to ensure high fidelity of tRNA charging; if the tRNA is found to be improperly charged, the aminoacyl-tRNA bond is hydrolyzed. SLM5 acts to attach asparagine residues to its cognate tRNA.

Also known as:

AI875199; AsnRS; Asparagine tRNA ligase 2; Asparagine tRNA ligase 2 mitochondrial; Asparagine tRNA 天冬氨酰tRNA连接酶2抗体ligase; Asparaginyl tRNA synthetase 2; Asparaginyl tRNA synthetase 2 mitochondrial; FLJ23441; MGC125113; MGC41336; NARS 2; Probable asparaginyl tRNA synthetase; Probable asparaginyl tRNA synthetase mitochondrial; RGD1305145; SLM5.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human NARS2.

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天冬氨酰tRNA连接酶2抗体Predicted Molecular Weight: 52kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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