磷脂酸磷酸酶2b抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 磷脂酸磷酸酶2b抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Phosphatidic acid phosphatase type 2b (PPAP2b) is a member of the phosphatidic acid phosphatase (PAP) family that function in de novo synthesis of glycerolipids as well as in receptor activated signal transduction mediated by phospholipase D. PAP2b catalyzes the conversion of phosphatidic acid to diacylglycerol and hydrolyzes lysophosphatidic acid,磷脂酸磷酸酶2b抗体  ceramide-1-phosphate and sphingosine-1-phosphate. It is a homodimer glycoprotein localized at the cell plasma membrane. Expression promotes adhesion, spreading, and tyrosine phosphorylation of Fak, Shc, Cas and paxillin in endothelial cells. PAP2b induced cell-cell interactions regulate specific intracellular signaling pathways that involve p120-catenin, Fak, Akt, and GSK3? protein kinases.

磷脂酸磷酸酶2b抗体 Also known as:

Dri42; Lipid phosphate phosphohydrolase 3; LPP3; PAP 2b; PAP2 beta; PAP2b; Vascular endothelial growth factor and type I collagen inducible protein; VCIP.

Specificity:

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Rabbit Polyclonal IgG,磷脂酸磷酸酶2b抗体  affinity purified by Protein A.

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Reacts with: Human, Mouse, Dog, Pig, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human PAP2B.

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Predicted Molecular Weight: 34kDa.

磷脂酸磷酸酶2b抗体 Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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