磷酸化3磷酸肌醇依赖性蛋白激酶1抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化3磷酸肌醇依赖性蛋白激酶1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt 磷酸化3磷酸肌醇依赖性蛋白激酶1抗体inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

磷酸化3磷酸肌醇依赖性蛋白激酶1抗体Also known as:

PDPK1(phospho S393); 3 phosphoinositide dependent protein kinase 1; hPDK 1; hPDK1; MGC20087 MGC35290; PDK 1; PDPK 1; PDPK1; PkB kinase; PkB kinase like gene 1; PkB like 1; PkB like; PRO0461; PDPK1_HUMAN.

Specificity:

●

Rabbit Polyclonal IgG,磷酸化3磷酸肌醇依赖性蛋白激酶1抗体 affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, .

●

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human PDPK1 around the phosphorylation site of Ser393.

●

磷酸化3磷酸肌醇依赖性蛋白激酶1抗体Predicted Molecular Weight: 61kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

kl025Hu01神经介素U(NMU)多克隆抗体Polyclonal Antibody to Neuromedin U (NMU)

kl027Hu01泛素激活酶样蛋白(UBE1L)多克隆抗体Polyclonal Antibody to Ubiquitin Activating Enzyme E1 Like Protein (UBE1L)

kl032Hu01磷脂酰肌醇蛋白聚糖1(GPC1)多克隆抗体Polyclonal Antibody to Glypican 1 (GPC1)

kl032Mu01磷脂酰肌醇蛋白聚糖1(GPC1)多克隆抗体Polyclonal Antibody to Glypican 1 (GPC1)

kl033Hu01Dickkopf相关蛋白2(DKK2)多克隆抗体Polyclonal Antibody to Dickkopf Related Protein 2 (DKK2)

kl036Hu01生长激素受体(GHR)多克隆抗体Polyclonal Antibody to Growth Hormone Receptor (GHR)

kl038Hu01谷氨酸半胱氨酸连接酶(GCLM)多克隆抗体Polyclonal Antibody to Glutamate Cysteine Ligase, Modifier Subunit (GCLM)

kl039Hu01表面活性物质关联蛋白D(SPD)多克隆抗体Polyclonal Antibody to Surfactant Associated Protein D (SPD)

kl039Mu01表面活性物质关联蛋白D(SPD)多克隆抗体Polyclonal Antibody to Surfactant Associated Protein D (SPD)

kl039Ra01表面活性物质关联蛋白D(SPD)多克隆抗体Polyclonal Antibody to Surfactant Associated Protein D (SPD)

kl040Hu01波形蛋白(VIM)多克隆抗体Polyclonal Antibody to Vimentin (VIM)

kl040Mu01波形蛋白(VIM)多克隆抗体Polyclonal Antibody to Vimentin (VIM)

kl041Hu01玻连蛋白(VTN)多克隆抗体Polyclonal Antibody to Vitronectin (VTN)

kl042Hu01整合素β1(ITGβ1)多克隆抗体Polyclonal Antibody to Integrin Beta 1 (ITGb1)

kl045Hu01蛋白激酶Cβ1(PKCβ1)多克隆抗体Polyclonal Antibody to Protein Kinase C Beta 1 (PKCb1)

kl045Ra01蛋白激酶Cβ1(PKCβ1)多克隆抗体Polyclonal Antibody to Protein Kinase C Beta 1 (PKCb1)

kl049Hu01三叶因子1(TFF1)多克隆抗体Polyclonal Antibody to Trefoil Factor 1 (TFF1)

kl050Hu01雌激素受体α(ERα)多克隆抗体Polyclonal Antibody to Estrogen Receptor Alpha (ERa)

kl050Mu01雌激素受体α(ERα)多克隆抗体Polyclonal Antibody to Estrogen Receptor Alpha (ERa)

kl050Ra01雌激素受体α(ERα)多克隆抗体Polyclonal Antibody to Estrogen Receptor Alpha (ERa)

kl051Hu01胆囊收缩素B受体(CCKBR)多克隆抗体Polyclonal Antibody to Cholecystokinin B Receptor (CCKBR)

kl053Hu01细胞色素P450家族成员7A1(CYP7A1)多克隆抗体Polyclonal Antibody to Cytochrome P450 7A1 (CYP7A1)

kl053Mu01细胞色素P450家族成员7A1(CYP7A1)多克隆抗体Polyclonal Antibody to Cytochrome P450 7A1 (CYP7A1)