磷酸化Rho相关蛋白激酶1抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化Rho相关蛋白激酶1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also磷酸化Rho相关蛋白激酶1抗体 essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq].

磷酸化Rho相关蛋白激酶1抗体Also known as:

p-ROCK1(Thr455/Ser456); p160 ROCK1; p160ROCK; Renal carcinoma antigen NY REN 35; Rho associated coiled coil containing protein kinase 1; Rho associated protein kinase 1; Rho-associated coiled-coil containing protein kinase 1; ROCK1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,磷酸化Rho相关蛋白激酶1抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human ROCK1 around the phosphorylation site of Thr455/Ser456.

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Predicted Molecular Weight: 158kDa.

磷酸化Rho相关蛋白激酶1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-300  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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