磷酸化蛋白酪氨酸磷酸酶2抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化蛋白酪氨酸磷酸酶2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This磷酸化蛋白酪氨酸磷酸酶2抗体 PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

磷酸化蛋白酪氨酸磷酸酶2抗体Also known as:

SHP2 (phospho Y582); p-SHP2 (phospho Y582); BPTP 3; BPTP3; CFC; MGC14433; Noonan syndrome 1 protein tyrosine phosphatase 2C; NS1; OTTHUMP00000166107; OTTHUMP00000166108; Protein tyrosine phosphatase 2; Protein tyrosine phosphatase 2C; Protein tyrosine phosphatase non receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTN11_HUMAN; PTP 1D; PTP 2C; PTP-1D; PTP-2C; PTP1D; PTP2C; PTPN11; SAP2;磷酸化蛋白酪氨酸磷酸酶2抗体 SH PTP2; SH PTP3; SH-PTP2; SH-PTP3; SH2 domain containing protein tyrosine phosphatase 2; SHIP2; SHP 2; SHP-2; Shp2; SHPTP 2; SHPTP2; SHPTP3.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human SHP2 around the phosphorylation site of Tyr582.

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磷酸化蛋白酪氨酸磷酸酶2抗体Predicted Molecular Weight: 68kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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