磷酸化神经色氨酸羟化酶2抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化神经色氨酸羟化酶2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH), tryptophan hydroxylase (TPH) and tryptophan hydroxylase 2 (TPH2) comprise a small family of monooxygenases that catalyze the rate-limiting step in the catabolism of aromatic L-amino acids and utilize tetrahydropterine as a cofactor. TPH2 is highly expressed in the central nervous system (CNS), mainly in the brain. TPH2 catalyzes the first step in the biosynthesis of serotonin in the CNS 磷酸化神经色氨酸羟化酶2抗体and melatonin in the pineal gland, and may be involved in the pathology of several neuropsychiatric disorders. Glucocorticoid-mediated reduction of TPH2 is associated with the etiology of mood disorders, specifically psychotic major depression, and TPH2 may be related to dysregulation of serotonin neurotransmission in the brain which commonly leads to suicidal behavior.

磷酸化神经色氨酸羟化酶2抗体Also known as:

TPH2 (phospho S19); p-TPH2 (phospho S19); MGC138871; ADHD7; FLJ37295; HGNC:20692; MGC138872; Neuronal tryptophan hydroxylase; NTPH; TPH 2; Tph2; TPH2_HUMAN; TRPO; Tryptophan 5-hydroxylase 2; Tryptophan 5-monooxygenase 2; Tryptophan hydroxylase 2; Tryptophan pyrrolase; Tryptophanase.

Specificity:

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Rabbit Polyclonal IgG,磷酸化神经色氨酸羟化酶2抗体 affinity purified by Protein A.

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Reacts with: Human, Dog, Horse, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human TPH2 around the phosphorylation site of Ser19.

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磷酸化神经色氨酸羟化酶2抗体Predicted Molecular Weight: 56kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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